A practice oriented, interactive platform to promote Replacement, Reduction and Refinement in animal experiments.
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April 12, 2018

Swiss 3Rs Competence Center (3RCC) update!
The idea for Swiss competence center dealing solely with the 3Rs was conceived in July 2015 when the Federal Council published a report on the subject of the 3Rs, in which it proposed various measures for further promotion of the 3Rs. As a follow up to this report, in the spring of 2016, the federal government commissioned swissuniversities to come up with a structure and mission to achieve these ambitious goals and the 3Rs competence center (3RCC) was conceptualised with an aim to promote the 3Rs on a sustainable basis in collaboration with industry,universities, government and animal welfare associations in order to provide services for enforcement agencies, industry and universities in the field of 3Rs training and continuing education and to improve international scientific networking on the topic.
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November 7, 2017

Share aged mice with ShARM
ShARM is a not for profit organisation, open to all scientific investigators in the UK and overseas, aiming to accelerate research into ageing by facilitating the sharing of resources. ShARM provides immediate and cost effective access to aged murine models and their tissues, and promotes the networking for researchers via its online collaborative environment.
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November 3, 2017

SGV Annual meeting 28th & 29th November!

Date: 28th & 29th November

Time: 9:00am Location: Technopark, Zurich Programme and registration information available on the SVG website  

November 2, 2017

Alternative mouse handling
Alternative handling techniques for improved experimental standardisation, reproducibility and reduced stress in laboratory mice Despite decades of artificial selection and inbreeding, laboratory mice retain the fight or flight response to restraint which kept enough of their ancestors alive during predation attempts to genetically cement it into their innate behavioural repetoire. Even what might seem like a light form of handling, such as picking up the mouse by its tail, can be a source of great stress to the individual, particularly when the experience is novel.
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November 2, 2017

DART 3R DEVELOPMENTS
All DART (Developmental and Reproductive Toxicity) tests demand large numbers of animals, as parental and offspring generations are involved, and depending on circumstances, developmental toxicity studies can be required to be executed in two species (i.e.
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October 20, 2017

Farewell 3R Research foundation
Join us to celebrate! The 3R Research Foundation ends its tireless commitment after 30 years and will be replaced by the 3R-Kompetenzzentrum of swissuniversities. The BLV is pleased to invite you to a farewell synopsium for the foundation.
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September 29, 2017

Are you aware of PREPARE?
As part of ongoing efforts to reduce the number of animals and increase reproducibility of animal research, a group of experts led by the Secretary of Norecopa (Norway´s National Consensus Platform for the advancement of the 3R´s) has produced a set of guidelines for planning animal experiments:   PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence)   These guidelines for planning animal experiments complement the ARRIVE (https://www.nc3rs.
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May 12, 2017

Animal Free Research: Call for project proposals
The overall aim of the funding opportunity is to support researchers who want to develop and/or implement a 3R-relevant project. The focus lies on replacement/reduction.
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May 12, 2017

22.5.2017 Prof. Dr. Gerald Schwank
Organe aus dem Reagenzglas - Nutzen für Mensch und Tier Prof. Dr.
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April 10, 2017

Optimizing reliability of mouse performance in behavioral testing
The major role of non-aversive handling Abstract: Handling laboratory animals during test procedures is an important source of stress that may impair reliability of test responses. Picking up mice by the tail is aversive, stimulating stress and anxiety.
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April 10, 2017

N3CR News: How serious are we about asepsis for rodent surgery?
The National Centre for the Replacement, Refinement & Reduction of animal Research (NC3R) has recently published a blog from Prof. Paul Flecknell, Newcastle University on the issue of aseptic surgery.
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April 10, 2017

NC3R News: 10 ways your 3R funding application could be failing.
To help applicants avoid common pitfalls encountered during application process for 3R projects, the top ten tips were gathered by the NC3R funding team and panel members. Top ten tips for successful application.
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January 17, 2017

Surgical practice without live animal - Registration is now open!
This new course of surgical practice is organized by WASP science (Without Animal Suffering and Pain) and takes place from March 15 to 17 in Lyon. Intended for technicians and researchers, it is essentially practical and accommodates no more than 12 people.
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January 3, 2017

3R World Congress 2017
Tenth World Congress - Alternatives and animal use in Life Sciences Seattle, Washington, USA Save the Date for The 3Rs in Action! August 20-24, 2017  

December 19, 2016

Do you know...ALTEX?
ALTEX is devoted to the publication of research on the development and promotion of alternatives to animal experiments according to the 3Rs concept of Russell and Burch: Replace, Reduce, and Refine. ALTEX publishes original articles, short communications, and reviews, as well as news and comments, meeting reports, and book reviews.
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December 19, 2016

40 years Animalfree Research
Animal Free Research is a society for animal welfare as highest priority. It was founded in 1976 by Susi Goll and Irene Hagmann with the motivation is to replace animal experiments.
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September 15, 2016

Animatch Switzerland
Over the last decades the number of animals used for scientific purposes has increased dramatically. Not all of these animals participate in an actual experiment.
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July 1, 2016

The animal experimentation quandary: stuck between legislation and scientific freedom
More research and engagement by scientists is needed to help to improve animal welfare without hampering biomedical research. Read full commentary here

July 1, 2016

Electroencephalographic responses to tail clamping in anaesthetized rat pups
The authors investigated electroencephalographic (EEG) responses to tail clamping in lightly anaesthetized rat pups (5–22 days) in order to determine the ontogeny of EEG activity and at what age they may be capable of experiencing pain. Median frequency (F50) and spectral edge frequency (F95) of the power spectrum in the range of 1–30 Hz were determined before and after the application of a noxious stimulus and power spectra were compared by multivariate analysis.
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July 1, 2016

Comparative analysis and physiological impact of different tissue biopsy methodologies used for the genotyping of laboratory mice
Genotyping of genetically modified mice and control of authenticity of the genetic background of congenic or coisogenic strains by polymerase chain reaction (PCR) is a routine procedure that can be performed with different tissue biopsies causing variable grades of trauma. In this study, some invasive and non-invasive sampling methods were compared, with the main focus on the impact on animal physiology.
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