Das Bundesamt für Lebensmittelsicherheit und Veterinärwesen hat beim Staatssekretariat für Bildung, Forschung und Innovation einen Vorschlag für ein nationales Forschungsprogramm für 3R eingereicht. Ziel dieses NFP-Vorschlags ist es, in der Schweiz eine 3R-Kultur in der Wissenschaft zu etablieren (D, F, E).
Die Rektorenkonferenz der Schweizerischen Hochschulen haben Grundsätze zur tierexperimentellen Forschung publiziert mit dem Ziel, Verbesserungen im Sinne der 3R zu fördern (D, E).
The second day of the Annual Meeting 2013 of the Swiss Laboratory Animal Association was dedicated to 3R aspects. Nine talks focused on various aspects of 3R implementation, ranging from political statements, presentation of alternative methods to planning and publication aspects of animal experiments.
In this provocative essay the author, John P.A. Ioannidis, examines and discusses the increasing concern that many published research findings are false.
In this article in Nature Reviews – Neuroscience the authors explain why small sample size undermines the reliability findings.
The Rectors Conference of the Swiss Universities (CRUS) has issued principles regarding animal experimentation (adopted 17/01/2013).
A sore system for the monitoring of mice initially published by the University of Virginia has been adapted and been modified by the Institut of Laboratory Animal Science of the University of Zurich. In particular the termination criteria have been reset to an earlier point.
The obligation to minimize or eliminate unnecessary pain and distress that animals may experience when used in research, research training, and biological testing activities is clearly stated in the USDA Animal Welfare Act and the PHS Policy on Humane Care and Use of Laboratory Animals. To that end, the Institutional Animal Care and Use Committee (IACUC) at the University of Virginia reviews all proposed and current animal use to ensure that we, as an institution, meet both our legal and ethical obligations with regard to animal research.
Vasectomy is a surgical procedure (severity level of 2) which until now is indispensable for the preparation of males which are subse‐ quently used to induce pseudopregnancy in foster females. Such females are required for strain rederivation by embryo transfer (ET) as well as other techniques that involve ET such as the production of transgenic and “knock‐ out” mice. We have recently refined all ET‐ dependant methods by generating a transgenic mouse strain carrying a dominant male‐specific sterility trait. Males from such a strain could be used directly to induce pseudopregnancy in females thus making the vasectomy procedure redundant. …
According to a new ordinance of the Federal Veterinary Office (BVET) issued May 1st, 2010, marking and biopsy taking of mice will have to be combined. Apart from ear punches, a method of choice is the clipping of toe tips of newborn mice. However, the method is dis‐ cussed controversially from an animal welfare point of view, both by authorities and the public.